PT-141 for Men
What is PT-141?
PT-141 was developed from the peptide Melanotan 2, which is a synthetically produced variant of a
peptide hormone naturally produced in the body that stimulates melanogenesis that is known as alpha-
Melanocyte stimulating hormone. PT-141 has been shown in studies to provide libido-enhancing effects by
activating the melanocortin receptors MC1R and MC4R, without tanning the skin.
PT-141 is a potential remedy for the treatment of female sexual dysfunction and male erectile dysfunction.
Studies have shown that PT-141 does not act on the vascular system, but may increase sexual desire
through the nervous system.
Patient Benefits Over Time May Include:
Typical Prescribing Protocol for Men:
Males with no history of ED may begin with 1mg (0.1mL) via subcutaneous injection in the lower right
quadrant of abdomen at least 45 minutes prior to sexual activity (titrating dose upward to effect as needed
or tolerated).
Males with a history or diagnosis of ED with inadequate response to Sildenafil 100mg may begin with 4mg
(0.4mL) via subcutaneous injection in the lower right quadrant of abdomen approximately 45 minutes prior
to sexual activity (titrating dose upward to effects as needed or tolerated).
Side effects may include: nausea, flushing and headache.