What is PT-141?
PT-141 was developed from the peptide Melanotan 2, which is a synthetically produced variant of a peptide hormone naturally produced in the body that stimulates melanogenesis that is known as alphaMelanocyte stimulating hormone. PT-141 has been shown in studies to provide libido-enhancing effects by activating the melanocortin receptors MC1R and MC4R, without tanning the skin.
PT-141 is a potential remedy for the treatment of female sexual dysfunction and male erectile dysfunction. Studies have shown that PT-141 does not act on the vascular system, but may increase sexual desire through the nervous system.
Patient Benefits Over Time May Include:
Typical Prescribing Protocol:
Males with no history of ED may begin with 1mg (0.1mL) via subcutaneous injection in the lower right quadrant of abdomen at least 45 minutes prior to sexual activity (titrating dose upward to effect as needed or tolerated).
Males with a history or diagnosis of ED with inadequate response to Sildenafil 100mg may begin with 4mg (0.4mL) via subcutaneous injection in the lower right quadrant of abdomen approximately 45 minutes prior to sexual activity (titrating dose upward to effects as needed or tolerated).
Females with FSAD or HSDD may begin with 750mcg – 1mg (0.075mL – 0.1mL) via subcutaneous injection
(titrating dose upward to effect as needed or tolerated) at least 45 minutes prior to sexual activity. Recommended to use no more than two times per week.
Side effects for males and females may include: nausea, flushing and headache.
*Reference: Shadiack, AM, et al. “Melanocortins in the Treatment of Male and Female Sexual Dysfunction.” PubMed.gov, 2007, www.ncbi.nlm.nih.gov/pubmed/17584134. The information provided herein is for reference only and is not to be relieduponas making any representationas to the efficacy of any particular for mulations. The sample formulations described here in result from prescriptions previously ordered by professionals licensed to write prescriptions in their respectived is cipline. Nothing here in is intended to replace or influence the independent judgment of